How do you get the plasma gun in RE4?

Mastering the P.R.L. 412: Your Ultimate Guide to the Plasma Rifle in Resident Evil 4

So, you want to wield the P.R.L. 412, the devastating plasma rifle in Resident Evil 4? You’ve come to the right place! This guide will walk you through exactly how to unlock this powerhouse and answer all your burning questions about it.

The path to acquiring the P.R.L. 412 (Plasma Rifle Level 412) is straightforward but challenging. You must beat the main game on Professional mode. Once you accomplish this feat, the weapon becomes available for free at the start of a New Game Plus on any completed save file. You can find it available to select in your storage.

Now that you know how to unlock it, let’s dive deeper into the P.R.L. 412’s capabilities and address some common questions.

Frequently Asked Questions (FAQs) about the P.R.L. 412

What exactly is the P.R.L. 412?

The P.R.L. 412 is a unique, powerful weapon in Resident Evil 4 that fires concentrated bursts of plasma. It’s arguably the most potent weapon in the game, capable of obliterating most enemies with a single, charged shot. It also takes up 21 cells (3×7) in the Attache Case.

How do I use the P.R.L. 412 effectively?

The P.R.L. 412 has two firing modes. A charged shot unleashes a powerful blast that can instantly kill most enemies. Alternatively, a quick, uncharged shot functions similarly to a Flash Grenade, stunning nearby enemies and opening them up for melee attacks. The charged shot is the true strength of the weapon.

Does the P.R.L. 412 require ammo?

No! The P.R.L. 412 doesn’t use traditional ammunition. It operates on an internal energy system, meaning it has unlimited ammo. However, you still need to wait for it to recharge between shots, especially charged shots.

Is Professional mode really that hard?

Yes, Professional mode in Resident Evil 4 is significantly more challenging than other difficulties. Enemies hit harder, resources are scarcer, and auto-aim is disabled. Proper planning, resource management, and a solid understanding of enemy patterns are crucial for success.

Any tips for beating Professional mode to get the P.R.L. 412?

  • Master enemy patterns: Knowing when to dodge, parry, and attack is essential.
  • Conserve ammo: Don’t waste bullets on weaker enemies. Use your knife effectively.
  • Upgrade weapons wisely: Focus on upgrading weapons that you’re comfortable with and that are effective against a variety of enemies.
  • Utilize Flash Grenades: They’re invaluable for crowd control and stunning tough enemies.
  • Learn the layout: Familiarize yourself with the level design to avoid ambushes and find hidden resources.
  • Take advantage of New Game Plus: Use a completed save file with upgraded weapons and unlocked perks to make Professional mode slightly easier.

Can I use the P.R.L. 412 in my Professional mode playthrough?

No, that’s the catch! You can only unlock the P.R.L. 412 after beating Professional mode. You’ll have to rely on other weapons for your initial playthrough.

Are there other special weapons in Resident Evil 4?

Absolutely! Resident Evil 4 features a variety of special weapons, including the Chicago Sweeper (unlocked by completing Professional mode with an A rank) and the Handcannon (unlocked by completing the game on Professional mode without using any bonus weapons).

Which is better: the Chicago Sweeper or the P.R.L. 412?

It depends on your playstyle. The Chicago Sweeper is a rapid-firing submachine gun with infinite ammo (after its exclusive upgrade), making it great for sustained damage. The P.R.L. 412, on the other hand, is a one-shot killing machine, ideal for taking down tough enemies quickly. Most find the P.R.L. 412 to be more effective, though.

Where can I find other powerful weapons in the game?

The Merchant is your go-to source for powerful weapons. He offers a variety of options throughout the game, including the Broken Butterfly magnum and various shotguns and rifles. Explore thoroughly to find hidden weapons and treasures.

Is the P.R.L. 412 in the original Resident Evil 4, too?

Yes, the P.R.L. 412 is also present in the original Resident Evil 4, and the unlock conditions are the same: beat Professional mode.

Does the P.R.L. 412 work on all enemies?

The P.R.L. 412 is effective against most enemies, including bosses. However, some enemies, like Regeneradors, may require multiple shots or a specific strategy to defeat.

Can the P.R.L. 412 backfire?

No, the P.R.L. 412 doesn’t have any negative side effects or risks associated with its use. It’s a straightforward, powerful weapon.

What are the advantages of using the P.R.L. 412?

The primary advantage of the P.R.L. 412 is its immense damage output. It can eliminate most threats instantly, saving you ammo and reducing the risk of taking damage. It’s also very effective against bosses.

How does the P.R.L. 412 impact gameplay?

The P.R.L. 412 significantly alters the gameplay experience. It turns you into an unstoppable force, allowing you to breeze through sections that were previously challenging. This can make subsequent playthroughs more enjoyable and less stressful.

What other factors might I consider when planning a Professional mode run?

Consider joining online gaming communities and discords. Many resources are available to help you learn tips and tricks. Also, consider engaging with Games Learning Society, an organization that recognizes how games can create unique learning opportunities for everyone. Check them out at GamesLearningSociety.org.


The P.R.L. 412 is a testament to your skill and dedication in Resident Evil 4. Good luck unlocking this incredible weapon and enjoy the power it brings!

Successfully navigating the challenges of Professional mode not only unlocks the P.R.L. 412 but also enhances your understanding of the game’s mechanics.

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